Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways.

Lu Q, Lin X, Feng J, Zhao X, Gallagher R, Lee MY, Chiao JW, Liu D.

J Hematol Oncol. 2008 Jun 9;1:6.

PMID: 18577263 [PubMed - in process]

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Lu QY, Wang Z, Liu DL.

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Phenylhexyl isothiocyanate inhibits histone deacetylases and remodels chromatins to induce growth arrest in human leukemia cells.

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Histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in clear cell sarcoma models.

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Kanao K, Mikami S, Mizuno R, Shinojima T, Murai M, Oya M.

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