Table 1

IC₅₀ values of five methoxyflavone derivatives (2'-methoxyflavone, 5-methoxyflavone, DMF, TMF and PMF) in U937 and MOLT-4 cells

Methoxyflavone derivatives

IC₅₀ values (μ g/ml)*

U937 cells

MOLT-4 cells

2'-MF

31.61 ± 0.68

30.11 ± 0.16

5-MF

46.70 ± 1.60

26.39 ± 2.22

DMF

24.56 ± 2.80

48.13 ± 5.12

TMF

12.95 ± 0.48

30.44 ± 0.52

PMF

19.28 ± 0.55

31.16 ± 2.22

*Means and standard deviations are calculated from triplicates of three independent experiments.

Wudtiwai et al. Journal of Hematology & Oncology 2011 4:52   doi:10.1186/1756-8722-4-52