Table 2

Summary data of caspase-3 assay obtained from the flow cytometry analysis.

ATO Concentrations

Caspase-3 Negative Cells or Viable Cells

Caspase-3 Positive Cells or Apoptotic Cells

(Mean ± SD)%

(Mean ± SD)%

0 μg/mL

98.7 ± 0.6

1.1 ± 0.3

2 μg/mL

82.5 ± 8.9*

17.5 ± 8.9*

4 μg/mL

63.0 ± 2.4*

27.0 ± 2.4*

6 μg/mL

37.5 ± 8.8*

62.5 ± 8.8*

8 μg/mL

36.9 ± 9.7*

63.1 ± 9.7*

HL-60 promyelocytic leukemia cells were cultured in the absence or presence of ATO for 24 h as indicated in the Materials and Methods. Values are shown as means ± SDs of 3 replicates per experiment. *Significantly different at p < 0.05 to the control group.

Yedjou et al. Journal of Hematology & Oncology 2010 3:28   doi:10.1186/1756-8722-3-28