Figure 1.

Metaphase FISH maping of SYT, MALT1 and BCL2 on normal chromosome 18 (left). SYT and MALT1 FISH probes were "breakapart" dual color probes where the 3' end of the probe and the 5' end of the probe were labeled in two different colors (red and green) while the BCL2 was a locus specific probe labeled in red. The mapping of the loci on ring (18) (right) revealed all three loci intact with apparent no loss of genetic material from these loci on the ring 18 chromosome.