Table 4

Multivariate analysis of prognostic factors for stem cell transplant survival

Potential Risk Factors

Covariables

Hazard Ratio

95% CI

p-value


Iron Overload

Iron Score (0-3)

1.8

1.1 to 2.7

0.01

BMT Risk Factors

Age

<40, 40s, 50s, 60s

1.5

0.9 to 2.3

0.08

Gender

Male

0.8

0.4 to 1.6

0.54

Donor-Type

Auto, Sibling, MURD

1.6

0.9 to 2.7

0.06

Remission Status

CR1, CR2, No remission

1.1

0.7 to 1.7

0.70

End-Organ Damage

Heart Damage

Ejection Fraction

1.4

1.0 to 1.9

0.03

Liver synthetic function

INR

1.3

0.9 to 1.9

0.10

Hepatocellular damage

AST + ALT

0.8

0.6 to 1.2

0.32

Liver obstruction

Total Bilirubin

0.8

0.6 to 1.1

0.25

Inflammation

C-reactive protein

1.0

0.7 to 1.4

0.97


Potential risk factors were divided into ordered categorical variables when appropriate. The ejection fraction, INR, total transaminases, bilirubin, and C-reactive protein were categorized based on quartiles.

Storey et al. Journal of Hematology & Oncology 2009 2:44   doi:10.1186/1756-8722-2-44

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